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KMID : 0386720100220030227
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Journal of the Korean Hip Society
2010 Volume.22 No. 3 p.227 ~ p.233
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The Tribological and Lubrication Responses of a Cobalt-Chromium Femoral Head in Total Hip Arthroplasty
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Park Sung-Hoon
Duong Cong-Truyen
Lee Jae-Hoon
Cho Youn-Ho
Park Seung-Jae
Park Gun-Min
Chang Jun-Dong
Lee Sang-Soo
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Abstract
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Objectives: This study aimed at investigating the role of albumin as a boundary lubricant in the lubrication of the Co-Cr femoral head of artificial hip implants by measuring the tribological parameters of the Co-Cr femoral head with Atomic Force Microscope (AFM) techniques.
Methods: Samples were prepared from the main wear region of a Co-Cr femoral head from revision hip surgery. Two types of solutions were prepared as lubricants: PBS (Phosphate Buffered Saline) as a control solution and BSA (Bovine Serum Albumin) as a lubricant at concentrations of 10, 20, 30 and 40 mg/ml in PBS solution.
Results: There were statistically significant differences in the frictional coefficients (μ) of a Co-Cr head between the PBS control and all the concentrations of BSA (10, 20, 30, 40 mg/ml) (P<0.001). Similarly, there were statistically significant differences for the μ between the BSA concentrations of 10, 20, 30 and 40 mg/m for all the cases except between the BSA of 30 and 40 mg/ml (P<0.01).
Conclusions:There exists a maximum protein concentration of BSA to play a role as an effective boundary lubricant through adsorption on the surface of Co-Cr femoral head.
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KEYWORD
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Atomic force microscope (AFM), Bovine serum albumin (BSA), Boundary lubrication, Total hip arthroplasty, Co-Cr femoral head
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